Radioactive Iodine Ablation to Treat Thyroid Disease Pediatric Thyroid Center at CHOP 6 of 9
gt;gt; FOR SOME CONDITIONS OF THE THYROID, THERE ARE REALLY TWO APPROACHES. YOU CAN SURGICALLY REMOVE THE ENTIRE THYROID GLAND, OR YOU CAN TREAT IT WITH RADIOACTIVE IODINE TO BASICALLY ABLATE THE THYROID TISSUE. THE THYROID IS UNIQUE IN THE BODY IN THAT IT TAKES UP IODINE OR IODINERELATED COMPOUNDS SPECIFICALLY. gt;gt; SO RADIOACTIVE IODINE ABLATION,.
OR RADIOACTIVE IODINE TREATMENT, TAKES ADVANTAGE OF A NORMAL PROCESS WHERE THE THYROID CELLS, WHETHER THEY’RE THYROID CANCER OR NORMAL THYROID CELLS OR EVEN GRAVES’ CELLS, USUALLY TAKE IODINE TO MAKE THYROID HORMONE, BUT THIS TIME WE GIVE THE PATIENT RADIOACTIVE IODINE TO DESTROY THE THYROID GLAND. gt;gt; IN A PATIENT WITH GRAVES’ DISEASE,.
RADIOACTIVE IODINE TREATMENT IS MORE OF A DEFINITIVE THERAPY FOR THAT PATIENT, AND AT A LOWER DOSE CAN BE USED IN THIS MANNER, TO DESTROY THE THYROID CELLS FROM PRODUCING THE EXCESS THYROID HORMONE. gt;gt; WE’RE TRYING TO GET RID OF THE ENTIRE THYROID GLAND. SO IF YOU USE RADIOACTIVE IODINE, YOU’RE TRYING TO GIVE A BIG ENOUGH DOSE THAT YOU CAUSE SCARRING DOWN UNDER THE THYROID GLAND SO YOU GET RID.
OF THE GRAVES’ DISEASE. FOR RADIOACTIVE IODINE ABLATION, OFTENTIMES WE RESTRICT IT TO CHILDREN THAT ARE OVER AGE 5 AND MANY TIMES ACTUALLY OVER AGE 10, IF WE’RE GOING TO CONSIDER THEM FOR THAT TYPE OF THERAPY, COMPARED TO EITHER STAYING ON MEDICAL THERAPY OR SURGICAL INTERVENTION.
The most important lesson from 83000 brain scans Daniel Amen TEDxOrangeCoast
In this talk, I’m going to give you the single most important lesson my colleagues and I have learned from looking at 83,000 brain scans. But first, let me put the lesson into context. I am in the middle of seven children. Growing up, my father called me a maverick which to him was not a good thing. (Laughter) In 1972, the army called my number,.
And I was trained as an infantry medic where my love of medicine was born. But since I truly hated the idea of being shot at or sleeping in the mud, I got myself retrained as an Xray technician and developed a passion for medical imaging. As our professors used to say: quot;How do you know, unless you look?quot; In 1979, when I was a secondyear medical student, someone in my family became seriously suicidal, and I took her to see a wonderful psychiatrist.
Over time, I realized if he helped her, which he did, it would not only save her life, but it would also help her children and even her future grandchildren, as they would be shaped by someone who is happier and more stable. I fell in love with psychiatry because I realized it had the potential to change generations of people. In 1991, I went to my first lecture on brain SPECT imaging. SPECT is a nuclear medicine study that looks at the blood flow and activity,.
It looks at how your brain works. SPECT was presented as a tool to help psychiatrists get more information to help their patients. In that one lecture, my two professional loves, medical imaging and psychiatry, came together, and quite honestly, revolutionized my life. Over the next 22 years, my colleagues and I would build the world’s largest database of brain scans related to behavior.
On patients from 93 countries. SPECT basically tells us three things about the brain: good activity, too little, or too much. Here’s a set of healthy SPECT scans. The image on the left shows the outside surface of the brain, and a healthy scan shows full, even, symmetrical activity. The color is not important, it’s the shape that matters. In the image on the right, red equals the areas of high activity,.
And in a healthy brain, they’re typically in the back part of the brain. Here’s a healthy scan compared to someone who had two strokes. You can see the holes of activity. Here’s what Alzheimer’s looks like, where the back half of the brain is deteriorating. Did you know that Alzheimer’s disease actually starts in the brain 30 to 50 years before you have any symptoms? Here’s a scan of a traumatic brain injury.
Your brain is soft, and your skull is really hard. Or drug abuse. The real reason not to use drugs they damage your brain. Obsessiveâ€“compulsive disorder where the front part of the brain typically works too hard, so that people cannot turn off their thoughts. An epilepsy where we frequently see areas of increased activity. In 1992, I went to an allday conference on brain SPECT imaging,.