Let’s learn about 2 anterior pituitary hormones growth hormone and thyroid stimulating hormone The endocrine system consists of glands that secrete hormones that have a variety of functions in our bodies. Let’s look at one of these endocrine glands in a little bit of detail. The pituitary gland is located just under the brain in a part of the sphenoid bone known as the sella turcica. The pituitary gland is divided into anterior and posterior sections. Each of these sections work differently. The anterior pituitary contains blood vessels known as the hypophyseal portal system. This blood vessel system allows the hypothalamus.
To control the secretions of the anterior pituitary gland. There is always a 2step process for secreting anterior pituitary hormones. First a releasing hormone is secreted by the hypothalamus which travels through the blood vessel network to the anterior pituitary. Second a hormone is released by the anterior pituitary in response to the hypothalamic releasing factor. Let’s look at how this works in the secretion of Growth hormone. There are 2 hypothalamic releasing hormones that control the secretion of growth hormone. Growth hormone releasing hormone, secreted by the hypothalamus, facilitates the release.
Of growth hormone by the anterior pituitary. Another hypothalamic releasing hormone, somatostatin, has the opposite effect. Somatostatin inhibits the secretion of growth hormone by the anterior pituitary. Both growth hormone and somatostatin work to regulate the release of growth hormone. Growth hormone stimulates mitosis and differentiation of cells which results in growth. Too much growth hormone secretion causes a condition known as acromegaly or giantism. Too little growth hormone secretion causes impaired growth. Let’s look at another anterior pituitary hormone. This one is called thyroid stimulating hormone or TSH. There is also a 2 step process for releasing TSH.
Anatomy and Physiology of the Endocrine System Growth Hormone and Thyroid Stimulating Hormone
First of all, a hypothalamic releasing hormone called thyrotropin releasing hormone or TRH is released. TRH travels through the blood vessels system to the anterior pituitary and causes the release of TSH. TSH targets the thyroid gland and facilitates the release of 2 thyroid hormones T3 and T4. T3 is also known as triiodothyronine And T4 or thyroxine is also known as tetraiodothyronine. Both contain iodine which is required for making each hormone. T3 and T4 also work with Growth hormone to promote tissue growth. T3 and T4 work to control metabolism Too much T3 and T4 would cause an increase.